There are some severe acne that are difficult to treat.
At such cases many of the treatments fail to clear the skin.
Then there is one famous treatment called
This treatment results in the prolonged clearance of acne.
This can be permanent for some patients.
Isotretinoin is a synthetic isomer of retinoic acid .
It has the property of inhibiting sebaceous gland secretion .
Due to this,it is involved in the treatment of severe nodular acne.
A powerful vitamin A derivative used in the treatment of acne. It can promote scarring after skin resurfacing procedures.
The acne that causes deep, painful cysts and nodules are cleared through it.
One course of treatment needs about 4 to 5 months.
Sometimes the course takes less time or a bit more .
What is this isotretinoin?
A dermatologist prescribes an oral drug for the treatment of severe acne.
This drug is called " Isotretinoin ".
The inflammation of skin causes the acne.
The teenagers and sometimes the adults also get effected through acne.
Severe acne can cause permanent scarring of the skin.
An increased secretion of sebum from glands in the skin known as sebaceous glands causes the inflammation.
The inflammation is provoked by sebum.
This inflammation gets resolved with the formation of a keratinization.
It is believed that the isotretinoin reduces acne by reducing the secretion of sebum.
There can be less inflammation and keratinization if less sebum is secreted .
For what the isotretinoin is used for ?
The severe acne that is resistant to more conservative treatments such as drying agents, creams ,or topical suspensions or any oral antibiotics are treated with isotretinoin.
After one course of fifteen to twenty weeks of this treatment a complete remission or prolonged improvement has been seen in many patients.
Isotretinoin should be used only for severe resistant acne because it has serious side effects.
Isotretinoin can cause birth defects.
Isotretinoin can be sold only under a special program approved by the Food and Drug Administration called iPLEDGE.
Healthcare providers have the right to prescribe the isotretinoin and it can only be dispensed by pharmacies registered in iPLEDGE.
The brand names that are available for isotretinoin are:
Zenatane, Claravis, Sotret, Amnesteem, Myorisan, Absorica
Isotretinoin is available as a generic drug.
An individual needs a prescription for isotretinoin to purchase it.
The side effects of isotretinoin:
Some most common side effects of isotretinoin are:
dry skin,dry mouth,nosebleeds, itching, dry nose, cracks in the corners of the mouth , joint aches are also common.
Patients develope an increase in blood cholesterol and triglycerides through it.
Other side effects include:
headache, abnormal periods in females, increased triglycerides ,increased glucose levels, joint aches, edema , increased cholesterol, insomnia.
The serious side effects of isotretinoin include:
skin infections , hearing impairment , peeling , hepatitis , sun-sensitivity to drugs.
It causes birth defects if taken during pregnancy.
Isotretinoin acts as a wonder drug for acne.
Though it has lots of side effects, but
they can be avoided if taken under strict guidance of a dermatologist.